Free Radical Scavengers
Free radical scavengers are bioactive substances that eliminate reactive free radicals. Free radicals with unpaired electrons easily damage lipids, proteins and DNA, causing oxidative stress and cell aging.
Free radical scavengers neutralize radicals by donating electrons or hydrogen atoms to form stable inert compounds. Their scavenging capacity is measured by in vitro assays including DPPH and ABTS tests.
Common natural scavengers are polyphenols, flavonoids, vitamin C and vitamin E. They are widely studied for food preservation, cosmetic anti-oxidation and treatments for oxidative damage-related diseases.
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Free Radical Scavengers Related Products (379)
Related Products (379)
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MAO-B-IN-48
0 ImagesCat. No.: HY-175523MAO-B-IN-48 is a selective MAO-B inhibitor (IC50 = 0.09 μM, Ki = 0.02 μM). MAO-B-IN-48 exhibits inhibitory activity against hBChE (IC50 = 1.10 μM, Ki = 0.43 μM) and AChE (IC50 = 0.56 μM, Ki = 0.14 μM). MAO-B-IN-48 suppresses self-induced aggregation of toxic β-amyloid peptides and exerts antioxidant activity, including DPPH radical scavenging, CUPRAC copper ion reduction, and superoxide anion scavenging. MAO-B-IN-48 can be used for the study of Alzheimer's disease (AD).
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Bispyrayafoline
0 ImagesCat. No.: HY-N19719CAS No.: 1715114-37-6Bispyrayafoline is a pyrrolidone and antioxidant with an IC50 value of 13.85 μM against DPPH. Bispyrayafoline can be found in the leaves of Murraya koenigii (Linn.) Spreng. Bispyrayafoline's antioxidant activity is concentration-dependent but time-independent. Bispyrayafoline can be utilized in studies concerning oxidative damage.
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Odoratumone A
0 ImagesCat. No.: HY-N17551CAS No.: 1198306-72-7Odoratumone A (Compound 1/11) is a homoisoflavonoid identified in the rhizomes of Polygonatum odoratum (Mill.) Druce. Odoratumone A exhibits DPPH free radical scavenging activity (IC50 = 32.8 μg/mL) and exerts antioxidant properties. Odoratumone A is applicable for antioxidant research.
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1-O-Caffeoyl-3-O-galloyl-β-D-glucopyranose
0 ImagesCat. No.: HY-N19661CAS No.: 359819-42-41-O-Caffeoyl-3-O-galloyl-β-D-glucopyranose, a hydrolyzable tannin found in the rhizome of Balanophora harlandii, is a radical scavenger. 1-O-Caffeoyl-3-O-galloyl-β-D-glucopyranose scavenges DPPH (HY-N19661) radicals with a SC50 value of 17.3 μM. 1-O-Caffeoyl-3-O-galloyl-β-D-glucopyranose can be used for antioxidant research.
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5-O-(E)-p-Coumaroylquinic acid methyl ester
0 ImagesCat. No.: HY-N18243CAS No.: 1295570-97-6O-(E)-p-Coumaroylquinic acid methyl ester is a coumaric acid derivative found in the flowers of Vaccinium corymbosum. O-(E)-p-Coumaroylquinic acid methyl ester shows antioxidant effects and can be used for nutraceutical and functional food applications.
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DEMAMP
0 ImagesCat. No.: HY-181176DEMAMP is an antioxidant. DEMAMP exhibits scavenging effects on DPPH and H2O2 free radicals, with IC50 values of 0.60 and 0.48 mg/mL, respectively. Molecular docking simulations show that DEMAMP potently inhibits NADPH oxidase and the Mpro and RdRp proteins of SARS-CoV-2, and ADMET analysis confirms that it has favorable oral bioavailability. DEMAMP can be used in studies related to COVID-19.
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Pithecolobine
0 ImagesCat. No.: HY-N19846CAS No.: 22368-82-7Pithecolobine is a saponin-like alkaloid found in the bark, seeds, and leaves of Samanea saman. Pithecolobine can inhibit the growth of Gram-positive bacteria, Gram-negative bacteria, and pathogenic yeasts. Pithecolobine scavenges DPPH radicals. Pithecolobine can be used for the research of infections caused by pathogenic bacteria and yeasts.
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Methylnissolin-3-O-glucoside (Standard)
0 ImagesCat. No.: HY-N2473RCAS No.: 94367-42-7Methylnissolin-3-O-glucoside (Standard) is the analytical standard of Methylnissolin-3-O-glucoside (HY-N2473). This product is intended for research and analytical applications. Methylnissolin-3-O-glucoside is a flavonoid glycoside derivative of Methylnissolin (HY-N2484). Methylnissolin-3-O-glucoside is isolated from plants of the genus Astragalus (Leguminosae). Methylnissolin-3-O-glucoside effectively induces the expression of AKT/Nrf2 and its downstream target genes HO-1 and NQO1. Methylnissolin-3-O-glucoside inhibits TNF-α-induced phosphorylation of MEK and ERK. Methylnissolin-3-O-glucoside exhibits free radical scavenging activity. Methylnissolin-3-O-glucoside inhibits cell proliferation and cell migration. Methylnissolin-3-O-glucoside is used in research on esophageal squamous cell carcinoma.
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Jionoside D
0 ImagesCat. No.: HY-N0025CAS No.: 120406-34-0Jionoside D is a hydroxycinnamic acid ester with antioxidant property. Jionoside D has scavenging activity of intracellular reactive oxygen species (ROS) and of DPPH radical, and lipid peroxidation inhibitory activity. Jionoside D reduces the apoptotic cells induced by H2O2 in V79-4 cells. Jionoside D increases the activities of cellular antioxidant enzymes, SOD and catalase.
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(E)-Ferulic acid methyl ester
0 ImagesSynonyms: Methyl (E)-ferulate(E)-Ferulic acid methyl ester (Methyl (E)-ferulate) exhibits strong DPPH and ABTS+ radical scavenging activities.
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Patulitrin
0 ImagesCat. No.: HY-N10020CAS No.: 19833-25-1Patulitrin has scavenging effect in the DPPH radical. Patulitrin inhibits soybean lipoxygenase. Patulitrin also has antihypertensive effect. Patulitrin is an antioxidant flavonoid that can be isolated from Anthemis tinctoria.
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MPO-IN-6
0 ImagesCat. No.: HY-163332MPO-IN-6 (compound ADC) is an electrophile with good antioxidant and anti-inflammatory properties. MPO-IN-6 is a myeloperoxidase (MPO), dipeptidyl peptidase-4 (DPP-4), and α-glucosidase (α-GD) inhibitor with IC50s of 10 μM, 31.02 μM, and 46.05 μM, respectively. MPO-IN-6 is a potential cardiovascular preventive agent.
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Antioxidant agent-26
0 ImagesCat. No.: HY-189531CAS No.: 24978-47-0Antioxidant agent-26 is a DPPH free radical scavenger. Antioxidant agent-26 has broad-spectrum ultraviolet absorption properties and iron-reducing ability. Antioxidant agent-26 blocks the hERG potassium channel and reduces the tail current. Antioxidant agent-26 inhibits the proliferation of dermatophytes and tumor cells. Antioxidant agent-26 can be used in research related to T-cell leukemia, melanoma, and dermatophytosis.
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Luteolin 7-O-[β-D-apiofuranosyl-(1→6)]-β-D-glucopyranoside
![Luteolin 7-O-[β-D-apiofuranosyl-(1→6)]-β-D-glucopyranoside](https://file.medchemexpress.com/product_pic/hy-n13142.gif "Click to View Luteolin 7-O-[β-D-apiofuranosyl-(1→6)]-β-D-glucopyranoside Product Detail")
0 ImagesCat. No.: HY-N13142CAS No.: 211561-67-0Luteolin 7-O-[β-D-apiofuranosyl-(1→6)]-β-D-glucopyranoside (compound 3) is a flavonoid with antioxidant activity, which can be isolated from Margaritopsis carrascoana. Luteolin 7-O-[β-D-apiofuranosyl-(1→6)]-β-D-glucopyranoside has good DPPH free radical scavenging activity (IC50=0.188 mg/mL).
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Atherosperminine
0 ImagesAtherosperminine (Atherospermine) is a phosphodiesterase inhibitor. Atherosperminine inhibits growth of chloroquine-resistant Plasmodium falciparum. Atherosperminine scavenges DPPH free radicals, exhibits ferric reducing power, and chelates metal ions. Atherosperminine can be used for the research of malaria.
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Gliquidone sodium
0 ImagesCat. No.: HY-B1114ACAS No.: 62783-47-5Synonyms: AR-DF 26 sodiumGliquidone sodium (AR-DF 26 sodium) can bind to the pancreatic β-cells and increases insulin release to regulate blood glucose levels. Gliquidone sodium significantly decreases LPS (HY-D1056)-induced proinflammatory responses and inhibits ERK/STAT3/NF-κB phosphorylation in BV2 microglial cells. Gliquidone sodium can suppress microgliosis, microglial hypertrophy mediated by LPS, and proinflammatory cytokine COX-2 and IL-6 levels in murine model. Gliquidone sodium also exhibits good anticancer activity in lung carcinoma cells. Gliquidone sodium has antioxidant property. Gliquidone sodium can be studied in research for type 2 diabetes and cancers.
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Kelampayoside A
0 ImagesCat. No.: HY-N3424CAS No.: 87562-76-3Kelampayoside A, a natural compound, shows an EC50 value of 35.7 µg/mL in DPPH assay (antioxidative activity).
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ALR2-IN-9
0 ImagesCat. No.: HY-175862CAS No.: 2135481-84-2ALR2-IN-9 is a potent ALR2 inhibitor (IC50 = 21.8 nM) with excellent antioxidant activity (EC50 for DPPH radical scavenging = 2.8 μM). ALR2-IN-9 interacts directly with Reactive Oxygen Species (ROS)/Reactive Nitrogen Species (RNS) and interrupts the free radical chain reactions, and as an endogenous enzymatic antioxidant regulator, which regulates enzyme functions of CAT and SOD. ALR2-IN-9 regulates PI3K/Akt/Nrf2 pathway to attenuate hyperglycemia-mediated mitochondrial superoxide overproduction in vitro, and ameliorates CuSO4- and H2O2-induced oxidative stress in vivo. ALR2-IN-9 prolongs lifespan of C. elegans via the regulation of stress response genes such as PMK-1. ALR2-IN-9 is a promising anti-aging drug candidate. ALR2-IN-9 can be used for diabetic complication research.
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Actinoside E
0 ImagesCat. No.: HY-N17833CAS No.: 1340600-30-7Synonyms: Kaempferol 3-O-2,4'''-acetylrhamninosideActinoside E (Kaempferol 3-O-2,4'''-acetylrhamninoside) is a flavonoid triglycoside with antioxidant activity. Actinoside E scavenges DPPH, superoxide anion and hydroxyl radicals, and inhibits lipid peroxidation in mouse liver homogenate. Actinoside E can be used in studies related to myocardial ischemia.
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3′-Hydroxytectorigenin-7-O-β-D-xylosyl-(1→6)-β-D-glucopyranoside
0 ImagesCat. No.: HY-N13707CAS No.: 2408020-53-93′-Hydroxytectorigenin-7-O-β-D-xylosyl-(1→6)-β-D-glucopyranoside is an antioxidant that can be found in Pueraria montana var. lobata. It exhibits DPPH radical scavenging activity, with an IC50 value of 42 μg/mL.
